Optical resolution of asymmetric amines by preferential crystallization as lasalocid salts
โ Scribed by Westley, J. W.; Evans, R. H.; Blount, J. F.
- Book ID
- 126325585
- Publisher
- American Chemical Society
- Year
- 1977
- Tongue
- English
- Weight
- 543 KB
- Volume
- 99
- Category
- Article
- ISSN
- 0002-7863
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๐ SIMILAR VOLUMES
DL-Methionine hydrochloride (DL-Metโ HCl) was found to exist as a conglomerate, based on the infrared spectrum, solubility, and melting point. The optical resolution of DL-Metโ HCl was successfully achieved by preferential crystallization into Dand L-Metโ HCl. Treatment of the purified D-and L-Metโ HCl
## Abstract Gibbs energy of racemate formation, binary melting point diagram, and ternary solubility diagram suggested that 4โpiperidinium hydrogen (RS)โphenylsuccinate [(RS)โ4โMP salt] exists in a conglomerate. Appropriate conditions were explored on the basis of free energy of critical nucleation