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Optical mapping of lambda bacteriophage clones using restriction endonucleases

✍ Scribed by Meng, Xun; Benson, Kathrine; Chada, Kiran; Huff, Edward J.; Schwartz, David C.

Book ID
109915706
Publisher
Nature Publishing Group
Year
1995
Tongue
English
Weight
758 KB
Volume
9
Category
Article
ISSN
1061-4036

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The 2 micron circular DNA from S. cerevisiae has been cloned on bacteriophage lambda. The two forms of circular DNA which exist in equilibrium due to recombination between inverted repeat sequences were separated as stable clones, and a map of targets for restriction endonucleases EcoRI, HindIII and