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Optic Nerve Damage in Mice with a Targeted Type I Collagen Mutation

✍ Scribed by Mabuchi, Fumihiko ;Lindsey, James D. ;Aihara, Makoto ;Mackey, Mason R. ;Weinreb, Robert N.


Book ID
125535123
Publisher
Association for Research in Vision and Ophthalmology (ARVO)
Year
2004
Weight
262 KB
Volume
45
Category
Article
ISSN
1552-5783

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Q p e I1 collagenopathies consist of chondrodysplasias ranging from lethal to mild in severity. A large number of mutations has been found in the COL2A1 gene. Glycine substitutions have been the most common types of mutation. Genotype-phenotype cor- relations in type I1 collagenopathies have not bee