Opposite effects of serotonin and interferon-α on the membrane potential and function of human natural killer cells
✍ Scribed by Tibor Oláh; Imre Ocsovszki; Yvette Mándi; Rozália Pusztai; Márta Bakay; Elisabeth Balint
- Book ID
- 119987317
- Publisher
- Society for In Vitro Biology
- Year
- 2005
- Tongue
- English
- Weight
- 684 KB
- Volume
- 41
- Category
- Article
- ISSN
- 1475-2689
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Natural killer (NK) cells and NK cell activity were determined in three groups (newly diagnosed [n = 211, on therapy [n = 211, and off therapy [n = 181) of children with various types of malignant solid tumors and in a control group (n = 26) by means of Leu-7 and Leu-llb monoclonal antibodies and a
## Abstract Non‐toxic concentrations of retinoic acid (RA) inhibited the spontaneous activity of human natural killer (NK) cells. RA also inhibited the activation of human NK cells by treatment with partially purified human leukocyte interferon (HulFNα) or with inducers of IFNα and IFNγ. Full expre