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Opposite effects of native and oxidized lipoproteins on the activity of secretory phospholipase A2 group IIA

✍ Scribed by Aleksandra A. Korotaeva; Elena V. Samoilova; Aleksandra A. Pirkova; Vera A. Ameliushkina; Nina V. Prokazova; Vsevolod A. Tkachuk; Eugeny I. Chazov

Book ID
113865145
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
364 KB
Volume
90
Category
Article
ISSN
0090-6980

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## Abstract It is well known that the expression level of secretory group IIA phospholipase A~2~ (sPLA~2~‐IIA) is elevated in inflammatory diseases and lipopolysaccharide (LPS) up‐regulates the expression of sPLA~2~‐IIA in human umbilical vein endothelial cells (HUVECs). Recently, lower concentrati