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Opioid peptides decrease calcium-dependent action potential duration of mouse dorsal root ganglion neurons in cell culture

โœ Scribed by Mary Ann Werz; Robert L. Macdonald


Book ID
118867895
Publisher
Elsevier Science
Year
1982
Tongue
English
Weight
406 KB
Volume
239
Category
Article
ISSN
0006-8993

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Opioid agonists induced an increase in the intracellular free calcium concentration ([Ca2+Ii) or an inhibition of K+ (25 mM)-stimulated increase in [Ca2+Ii in different subsets of mouse dorsal root ganglion (DRG) neurons. The total neuronal population was grouped into three classes according to soma

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It is well established that neurons regulate the properties of both central and peripheral glial cells. Some of these neuro-glial interactions are modulated by the pattern of neuronal electrical activity. In the present work, we asked whether blocking the electrical activity of dorsal root ganglion