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Ophthalmological effects of 13-cis-retinoic acid therapy for acne vulgaris

โœ Scribed by Jane Milson; D.H. Jones; Kathrine King; W.J. Cunliffe


Book ID
108657596
Publisher
John Wiley and Sons
Year
1982
Tongue
English
Weight
64 KB
Volume
107
Category
Article
ISSN
0007-0963

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Sixteen patients with care acne conglobata, acne fulminans, acme tetrade were treated orally with 13-cis-retinoic acid, 1-2 mg/kg body weight for 12 weeks. A maintenance dose of 0.5 mg/kg in ten cases and the use of no further medication in six other cases for an additional 12 weeks followed. A 40%

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Ten patients treated with 13-cis-retinoic acid demonstrated a 70% reduction in sebum excretion on the forehead and cheek. An average reduction of 66% occurred in the 1st month, slowly increased to 70% by the 3rd month, and then remained constant for the final 2 months of therapy. Concomitant with th

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A follow-up was done on the patients of the German multicenter study with severe conglobate acne who had been treated with different dosages of 13-cisretinoic acid. Eighty-seven patients were monitored from 12 to 21 months. Optimal long-term therapeutic effects were obtained with an initial dose of