Ophthalmological and pharmacological stu
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I. Weisse; W. Hoefke; S. Greenberg; W. Gaida; H. Stötzer; H. Kreuzer
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Article
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1978
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Springer-Verlag
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English
⚖ 658 KB
Clonidine (0.3 mg/kg or more p.o.) induced corneal lesions in rats. Amitriptyline did not give rise to such alterations. Biomicroscopically, these clonidine-induced lesions presented as gradually differentiated focal opacities in the superficial layers of the corneal centre. The corneal alterations