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Operationally convenient asymmetric synthesis of (S)- and (R)-3-amino-4,4,4-trifluorobutanoic acid: Part I: Enantioselective biomimetic transamination of isopropyl 4,4,4-trifluoro-3-oxo-butanoate

โœ Scribed by Vadim A. Soloshonok; Hironari Ohkura; Manabu Yasumoto


Book ID
108170440
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
233 KB
Volume
127
Category
Article
ISSN
0022-1139

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๐Ÿ“œ SIMILAR VOLUMES


Operationally Convenient Asymmetric Synt
โœ Vadim A. Soloshonok; Hironari Ohkura; Manabu Yasumoto ๐Ÿ“‚ Article ๐Ÿ“… 2006 ๐Ÿ› John Wiley and Sons โš– 18 KB ๐Ÿ‘ 1 views

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Efficient synthesis of (2R,3S)-2-amino-3
โœ Chun-min Zeng; Sean A. Kerrigan; John A. Katzenellenbogen; Connie Slocum; Kyla G ๐Ÿ“‚ Article ๐Ÿ“… 2010 ๐Ÿ› Elsevier Science ๐ŸŒ French โš– 425 KB

An efficient synthesis of the non-proteinogenic amino acid (2R,3S)-4,4,4-trifluoro(OBn)-threonine is described. Starting with commercially available (S)-Garner's aldehyde, the desired amino acid was prepared as its hydrochloride salt in five steps and an overall yield of 33% (59% based on recovered