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Opening a New Can of Worms: A Large-Scale RNAi Screen in Planarians

✍ Scribed by Phillip A. Newmark


Book ID
116403864
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
106 KB
Volume
8
Category
Article
ISSN
1534-5807

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## Abstract Using a cascadic version of the stochastic tunneling method we perform an all‐atom database screen over 186,000 flexible ligands of the NCI 3D database against the thymidine kinase receptor. By analyzing the errors in the binding energy we demonstrate how the cascadic technique is super