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Open-loop control of specific growth rate in fed-batch cultures of recombinantE.coli

โœ Scribed by M. E. Gregory; C. Turner


Publisher
Springer-Verlag
Year
1993
Tongue
English
Weight
418 KB
Volume
7
Category
Article
ISSN
0951-208X

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โœฆ Synopsis


A computer-based algorithm was used for the open-loop control of specific growth rate in fedbatch cultures of recombinant E.coli.. The control of nutrient feed rate to an exponential trajectory resulted in growth of the culture at a constant specific growth rate. Stable specific growth rates between 0.08 and 0.4 h-1 were achieved.


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