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Open chromatin in pluripotency and reprogramming

โœ Scribed by Gaspar-Maia, Alexandre; Alajem, Adi; Meshorer, Eran; Ramalho-Santos, Miguel

Book ID
109959489
Publisher
Nature Publishing Group
Year
2010
Tongue
English
Weight
549 KB
Volume
12
Category
Article
ISSN
1471-0072

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## Abstract Induced pluripotent stem (iPS) cells can be generated from various embryonic and adult cell types upon expression of a set of few transcription factors, most commonly consisting of Oct4, Sox2, cMyc, and Klf4, following a strategy originally published by Takahashi and Yamanaka (Takahashi