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Chd1 regulates open chromatin and pluripotency of embryonic stem cells

✍ Scribed by Gaspar-Maia, Alexandre; Alajem, Adi; Polesso, Fanny; Sridharan, Rupa; Mason, Mike J.; Heidersbach, Amy; Ramalho-Santos, João; McManus, Michael T.; Plath, Kathrin; Meshorer, Eran; Ramalho-Santos, Miguel

Book ID
109898334
Publisher
Nature Publishing Group
Year
2009
Tongue
English
Weight
811 KB
Volume
460
Category
Article
ISSN
0028-0836

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## Abstract Embryonic stem cells have an unlimited potential for self‐renewal yet are pluripotent, capable of differentiating into three different germ layers and ultimately into multiple cell lineages. Key pluripotency specific factors maintain an undifferentiated ES cell phenotype while lineage s