OP-1 Enhances Dendritic Growth from Cerebral Cortical Neurons in Vitro
β Scribed by Peter Le Roux; Susana Behar; Dennis Higgins; Marc Charette
- Book ID
- 115607084
- Publisher
- Elsevier Science
- Year
- 1999
- Tongue
- English
- Weight
- 416 KB
- Volume
- 160
- Category
- Article
- ISSN
- 0014-4886
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Glutamate is an important regulator of dendrite development; however, during cerebral ischemia, massive glutamate release can lead to neurodegeneration and death. An early consequence of glutamate excitotoxicity is dendrite injury, which often precedes cell death. We examined the effect of glutamate
## Abstract Glutamate is an important regulator of dendrite development that may inhibit, (during ischemic injury), or facilitate (during early development) dendrite growth. Previous studies have reported mainly on the NβmethylβDβaspartate (NMDA) receptorβmediated dendrite growthβpromoting effect o