BMP-7 and Excess Glutamate: Opposing Effects on Dendrite Growth from Cerebral Cortical Neurons in Vitro

Effect of excess extracellular glutamate

Effect of excess extracellular glutamate on dendrite growth from cerebral cortical neurons at 3 days in vitro: Involvement of NMDA receptors

✍ Hubert Monnerie; Shalini Shashidhara; Peter D. Le Roux 📂 Article 📅 2003 🏛 John Wiley and Sons 🌐 English ⚖ 436 KB

Glutamate is an important regulator of dendrite development; however, during cerebral ischemia, massive glutamate release can lead to neurodegeneration and death. An early consequence of glutamate excitotoxicity is dendrite injury, which often precedes cell death. We examined the effect of glutamate