✦ LIBER ✦

Ontogeny of seizure incidence, latency, and severity in genetically epilepsy prone rats

✍ Scribed by Dr. Dennis L. Hjeresen; Joann E. Franck; Diane L. Amend

Publisher: John Wiley and Sons
Year: 1987
Tongue: English
Weight: 542 KB
Volume: 20
Category: Article
ISSN: 0012-1630
DOI: 10.1002/dev.420200312

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

The influence of manganese supplementati

The influence of manganese supplementation on seizure onset and severity, and brain monoamines in the genetically epilepsy prone rat

✍ James W. Critchfield; G.Frank Carl; Carl L. Keen 📂 Article 📅 1993 🏛 Elsevier Science 🌐 English ⚖ 825 KB

Human and experimental animal studies suggest a relationship between low Mn status and seizures. The genetically epilepsy prone rat (GEPR), which has low tissue Mn levels, was studied in the context of Mn supplementation. Manganese was provided at 45 pg/g diet (control) or 1000 pg/g diet (supplement

Sex-specific distinctions in audiogenic

Sex-specific distinctions in audiogenic convulsions exhibited by severe seizure genetically epilepsy-prone rats (GEPR-9S) 1

✍ Pravin K. Mishra; John W. Dailey; Charles E. Reigel; Margie L. Tomsic; Phillip C 📂 Article 📅 1988 🏛 Elsevier Science 🌐 English ⚖ 947 KB

Acute and chronic anticonvulsant effects

Acute and chronic anticonvulsant effects of d(−)CPPene in genetically epilepsy-prone rats

✍ Stuart E. Smith; Astrid G. Chapman 📂 Article 📅 1993 🏛 Elsevier Science 🌐 English ⚖ 667 KB

Acute administration (0.4-12 mumol/kg, i.p.) of the NMDA antagonist D(-)CPPene (3-(2-carboxypiperazin-4-yl)propenyl-1-phosphonic acid; molecular weight = 250.2) dose-dependently reduced the incidence of sound-induced clonic seizures in genetically epilepsy-prone (GEP) rats. The ED50 value against cl

Injections of noradrenergic and GABAergi

Injections of noradrenergic and GABAergic agonists into the inferior colliculus: effects on audiogenic seizures in genetically epilepsy-prone rats

✍ R.A. Browning; M.L. Lanker; C.L. Faingold 📂 Article 📅 1989 🏛 Elsevier Science 🌐 English ⚖ 831 KB

Genetically epilepsy-prone rats (GEPRs) which display tonic seizures (GEPR-9s) in response to acoustic stimulation were used in these studies. Other laboratories have shown that CEPR-9s have a reduced concentration of brain norepinephrine (NE). Previous reports have also indicated that audiogenie se

Effects of seizures on learning, memory,

Effects of seizures on learning, memory, and behavior in the genetically epilespy-prone rat

✍ Dr.; MD Gregory L. Holmes; MD James L. Thompson; Teresa A. Marchi; Pamela S. Gab 📂 Article 📅 1990 🏛 John Wiley and Sons 🌐 English ⚖ 882 KB

Induction of audiogenic seizures in norm

Induction of audiogenic seizures in normal and genetically epilepsy-prone rats following focal microinjection of an excitant amino acid into reticular formation and auditory nuclei

✍ Carl L Faingold; Maria H Millan; Cathy A.Boersma Anderson; Brian S Meldrum 📂 Article 📅 1989 🏛 Elsevier Science 🌐 English ⚖ 721 KB

An excitant amino acid (EAA), N-methyl-D-aspartate (NMDA), induces susceptibility to seizures when bilaterally microinjected into subcortical auditory nuclei of normal rats. Thirty-five percent of animals exhibit only audiogenic seizures (AGS) after infusions of NMDA into inferior colliculus (IC). I