We designed the present study to clarify whether the development of nephropathy was accelerated by a combination of hypertension and non-insulin-dependent diabetes. Spontaneously hypertensive rats with non-insulin-dependent diabetes induced by neonatal streptozotocin treatment (25.0-75.0 mg/kg) were
✦ LIBER ✦
Onset and evolution of nephropathy in rats with spontaneous diabetes mellitus
✍ Scribed by S. M. Daniele; S. Arriaga; S. M. Martínez; M. C. Tarrés; S. M. Montenegro; A. E. D’Ottavio; N. Hisano; J. C. Picena; L. Morisoli
- Book ID
- 105725988
- Publisher
- Springer
- Year
- 2000
- Tongue
- English
- Weight
- 766 KB
- Volume
- 56
- Category
- Article
- ISSN
- 1138-7548
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Rhubarb extract was given orally to rats with diabetic nephropathy induced by subtotal nephrectomy and injection of streptozotocin. As a result, high blood and urinary glucose levels, which were conspicuous in similarly treated rats that were not given rhubarb extract, were ameliorated. Furthermore,