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Only weak association between disease severity and HLA-DRB 1 genes in a Swiss population of rheumatoid arthritis patients

✍ Scribed by M. Seitz; M. Perler; W. Pichler


Publisher
Springer
Year
1996
Tongue
English
Weight
405 KB
Volume
16
Category
Article
ISSN
0172-8172

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HLA–DRB1 genotype associations in 793 wh
✍ James F. Fries; Frederick Wolfe; Raymond Apple; Henry Erlich; Teodorica Bugawan; 📂 Article 📅 2002 🏛 John Wiley and Sons 🌐 English ⚖ 78 KB

## Abstract ## Objective The HLA–DRB1 “shared epitope” (SE) genotypes are associated with rheumatoid arthritis (RA), but it remains controversial whether the association is with incidence, severity, or both, whether there are associations in seronegative patients, and whether different DRB1 allele