𝔖 Bobbio Scriptorium
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Only one of the origin binding forms of SV40 T antigen has helicase activity

✍ Scribed by Swati Palit Deb; Kathryn Partin


Book ID
117058639
Publisher
Elsevier Science
Year
1988
Tongue
English
Weight
404 KB
Volume
153
Category
Article
ISSN
0006-291X

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Structure-based design of a disulfide-li
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With the aim of forming the β€˜lock-washer’ conformation of the origin-binding domain of SV40 large T antigen in solution, using structure-based analysis an intermolecular disulfide bridge was engineered into the origin-binding domain to generate higher order oligomers in solution. The 1.7β€…Γ… resolutio