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One step enzymatic synthesis of dihydrosanguinarine from protopine

✍ Scribed by T. Tanahashi; M.H. Zenk


Book ID
104216844
Publisher
Elsevier Science
Year
1988
Tongue
French
Weight
244 KB
Volume
29
Category
Article
ISSN
0040-4039

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## Abstract A cascade of two enzymatic transformations is employed in a one‐pot synthesis of cephalexin. The nitrile hydratase (from __R. rhodochrous__ MAWE)‐catalyzed hydration of D‐phenylglycine nitrile to the corresponding amide was combined with the penicillin G acylase (penicillin amidohydrola