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Carbohydrates from glycerol: an enzymatic four-step, one-pot synthesis

✍ Scribed by Schoevaart, Rob; van Rantwijk, Fred; Sheldon, Roger A.


Book ID
115498284
Publisher
Royal Society of Chemistry
Year
1999
Tongue
English
Weight
38 KB
Volume
24
Category
Article
ISSN
1359-7345

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## Abstract A cascade of two enzymatic transformations is employed in a one‐pot synthesis of cephalexin. The nitrile hydratase (from __R. rhodochrous__ MAWE)‐catalyzed hydration of D‐phenylglycine nitrile to the corresponding amide was combined with the penicillin G acylase (penicillin amidohydrola