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One-step catalytic synthesis of 2,2,3-trimethylbutane from methanol

โœ Scribed by Kim, Leo; Wald, Milton M.; Brandenberger, Stanley G.


Book ID
121425704
Publisher
American Chemical Society
Year
1978
Tongue
English
Weight
271 KB
Volume
43
Category
Article
ISSN
0022-3263

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## Abstract The proton at 3โ€position of oxazepam (7โ€chloroโ€1,3โ€dihydroโ€3โ€hydroxyโ€5โ€phenylโ€2__H__โ€1,4โ€benzodiazepinโ€2โ€one) undergoes a deuterium exchange in deuterated alkaline methanol. A baseโ€catalyzed ketoโ€enol tautomerism is proposed to be responsible for the observed deuterium exchange. This si