One-Pot Three-Component Tandem Metathesis/Diels—Alder Reaction.
✍ Scribed by Hee-Yoon Lee; Hyoun Young Kim; Hyunsup Tae; Byung Gyu Kim; Jaeyoung Lee
- Publisher
- John Wiley and Sons
- Year
- 2004
- Weight
- 167 KB
- Volume
- 35
- Category
- Article
- ISSN
- 0931-7597
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## Abstract A hetero Diels‐Alder reaction with inverse electron demand between 4‐hydroxycoumarin, aromatic aldehydes and electron‐rich alkenes yielded a multitude of 2,4‐disubstituted 3,4‐dihydropyranocoumarins. This route opened an easy access to coumarin anticoagulants and provided a library of p
## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Starting from 4-hydroxy-5-methylcoumarin ( 7), (±)-preethulia coumarin (3) was synthesized in six steps and in 4% overall yield. The key synthetic procedure was a new type of Lewis acid catalysed, three-component Knoevenagel/hetero Diels-Alder reaction, which employs α-dicarbonyl com-Over the past f