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A library of pyranocoumarin derivatives via a one-pot three-component hetero diels-alder reaction

✍ Scribed by Giancarlo Cravotto; Gian Mario Nano; Silvia Tagliapietra; Giovanni Palmisano; Tullio Pilati

Publisher
Journal of Heterocyclic Chemistry
Year
2001
Tongue
English
Weight
81 KB
Volume
38
Category
Article
ISSN
0022-152X

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✦ Synopsis

Abstract

A hetero Diels‐Alder reaction with inverse electron demand between 4‐hydroxycoumarin, aromatic aldehydes and electron‐rich alkenes yielded a multitude of 2,4‐disubstituted 3,4‐dihydropyranocoumarins. This route opened an easy access to coumarin anticoagulants and provided a library of pyranocoumarin derivatives.

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