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One-pot three-component highly diastereoselective synthesis of isoindolin-1-one-3-phosphonates under solvent and catalyst free-conditions

✍ Scribed by José Luis Viveros-Ceballos; Carlos Cativiela; Mario Ordóñez

Book ID
113929534
Publisher
Elsevier Science
Year
2011
Tongue
English
Weight
959 KB
Volume
22
Category
Article
ISSN
0957-4166

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Uncatalyzed One-Pot Diastereoselective S
Uncatalyzed One-Pot Diastereoselective Synthesis of α-Amino Phosphonates Under Solvent-Free Conditions
✍ Gaurao D. Tibhe; Selene Lagunas-Rivera; Elena Vargas-Díaz; Oscar García-Barradas 📂 Article 📅 2010 🏛 John Wiley and Sons 🌐 English ⚖ 264 KB 👁 1 views

## Abstract Uncatalyzed one‐pot, three‐component reactions of aldehydes, chiral α‐methylamines, and dimethyl phosphite under solvent‐free conditions were used for the diastereoselective synthesis of α‐amino phosphonates. The reactions proceeded with extremely high efficiency under mild conditions a