One-Pot Synthesis of Symmetrical and Unsymmetrical Bisarylethynes by a Modification of the Sonogashira Coupling Reaction.
✍ Scribed by Matthew J. Mio; Lucas C. Kopel; Julia B. Braun; Tendai L. Gadzikwa; Kami L. Hull; Ronald G. Brisbois; Christopher J. Markworth; Paul A. Grieco
- Publisher
- John Wiley and Sons
- Year
- 2003
- Weight
- 252 KB
- Volume
- 34
- Category
- Article
- ISSN
- 0931-7597
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## Abstract Sonogashira coupling and the catalytic Glaser coupling are both catalyzed by the Pd–Cu complex couple and can be concatenated to a consecutive sequentially Pd/Cu‐catalyzed process in a one‐pot fashion, and air oxygen serves as the only oxidant in the second step. In a pseudo‐four‐compon
## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable v
## Abstract Sonogashira cross coupling of (het)aryl iodides (I) and (IV) with trimethylsilylacetylene (II) is successfully combined with Glaser coupling using air as oxidant to give symmetrical diaryldiacetylenes (III) and (V), resp., in a two‐step one‐pot sequence.