One-pot three-component synthesis of pyr
β
Hai-Ling Liu; Huan-Feng Jiang; Min Zhang; Wen-Juan Yao; Qiu-Hua Zhu; Zhou Tang
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Article
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2008
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Elsevier Science
π
French
β 138 KB
An efficient and general one-pot procedure for the synthesis of pyrazoles from acid chlorides, terminal alkynes and hydrazines was described via a coupling and cyclocondensation sequence. Acid chlorides coupled with terminal alkynes to give a,b-unsaturated ynones, and in situ converted into pyrazole