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One-Pot Synthesis of Polysubstituted Pyrimidines.

✍ Scribed by Alexander S. Kiselyov


Publisher
John Wiley and Sons
Year
2005
Weight
28 KB
Volume
36
Category
Article
ISSN
0931-7597

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## Abstract A tandem one‐pot synthesis of polysubstituted 1,3‐thiazines has been developed by reacting with cyanoacetamide and isothiocyanate derivatives to give rise to 2‐cyano‐3‐mercaptoacrylamides, which are trapped __in situ__ by various aldehydes or diversely substituted ketones through interm