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ChemInform Abstract: An Efficient Four-Component, One-Pot Synthesis of Polysubstituted Pyrimidines in Water.

✍ Scribed by Zhongqing Wang; Zemei Ge; Tieming Cheng; Runtao Li

Publisher
John Wiley and Sons
Year
2009
Weight
20 KB
Volume
40
Category
Article
ISSN
0931-7597

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An Efficient Four-Component, One-Pot Syn
An Efficient Four-Component, One-Pot Synthesis of Poly-Substituted Pyrimidines in Water
✍ Zhongqing WANG; Zemei GE; Tieming CHENG; Runtao LI πŸ“‚ Article πŸ“… 2009 πŸ› John Wiley and Sons 🌐 English βš– 75 KB

## Abstract An efficient environmentally friendly synthesis of poly‐substituted pyrimidines has been developed via a four‐component, one‐pot reaction of malononitrile, carbon disulfide, alkyl halide and __S__‐alkylisothiouronium salt in water at room temperature. Water as solvent, mild reaction con