One-Pot Synthesis of Amine-Substituted Aryl Sulfides and Benzo[ b ]thiophene Derivatives
β Scribed by Duan, Zhongyu; Ranjit, Sadananda; Liu, Xiaogang
- Book ID
- 120427425
- Publisher
- American Chemical Society
- Year
- 2010
- Tongue
- English
- Weight
- 598 KB
- Volume
- 12
- Category
- Article
- ISSN
- 1523-7060
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π SIMILAR VOLUMES
This communication describes an efficient one-pot procedure for the synthesis of 2-arylbenzo[b]thiophene derivatives via reaction of o-halo or nitro aryl carbonyl compounds with benzyl mercaptans in the presence of an excess of anhydrous K 2 CO 3 at elevated temperature.
Rcgiosclcctive synthesis of hitherto unreported pyrano[3,2-/]benzo [b]thiophme derivatives (Sa-f) in 90-95 % yields are reported by the application of a less studied rearrangemont of 6-(4-aryloxybut-2-ynylthio)[ 1 ]benzopyran-2-unes (fat-f) via oxidation with m-chioroparoxybenzoic acid followed by t