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One-Pot Synthesis of 2-Amino-4-aryl-5-oxo-5,6,7,8-tetrahydro-4H-1-benzopyran-3-carbonitriles in Aqueous Media.

✍ Scribed by Daqing Shi; Jie Mou; Qiya Zhuang; Xiangshan Wang

Publisher: John Wiley and Sons
Year: 2005
Weight: 17 KB
Volume: 36
Category: Article
ISSN: 0931-7597
DOI: 10.1002/chin.200525133

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## Abstract A facile synthesis of __trans__ isomers of 4‐aryl‐3‐methyl‐6‐oxo‐4,5,6,7‐tetrahydro**‐**2__H__**‐**pyrazolo[3,4‐__b__]pyridine‐5‐carbonitriles via three‐component condensation reaction of an aldehyde, 3‐amino‐5‐methylpyrazole and ethyl cyanoacetate in acetonitrile has been developed und