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One-pot synthesis of 2-alkyltetrahydropyran-3-ones from 3-nitro-5,6-dihydro-4H-pyran and grignard reagents

✍ Scribed by R. Menicagli; V. Guagnano; S. Samaritani


Publisher
Elsevier Science
Year
1995
Tongue
French
Weight
156 KB
Volume
36
Category
Article
ISSN
0040-4039

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## Abstract 2‐Aryl‐2,3‐dihydro‐4__H__‐pyran‐4‐ones were prepared in one step by cyclocondensation of 1,3‐diketone dianions with aldehydes. The use of HCl (10%) for the aqueous workup proved to be very important to avoid elimination reactions of the 5‐aryl‐5‐hydroxy 1,3‐diones formed as intermediate