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One-pot synthesis of 1,5-diaza-2,6-cyclooctadiene-3,7-dicarboxylates through a multiple-component reaction

✍ Scribed by Li, Yufeng; Wang, Xinglong; Li, Wei; Wu, Zhengguang; Shi, Jie; Ma, Hongfei


Book ID
125386632
Publisher
Elsevier Science
Year
2014
Tongue
English
Weight
460 KB
Volume
30
Category
Article
ISSN
1005-9040

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## Abstract magnified image The reactive zwitterionic 1 : 1 intermediate **6** generated __in situ__ from the reaction between an isocyanide **2** and a dialkyl acetylenedicarboxylate (=dialkyl but‐2‐ynedioate) **3** was trapped by an __N__‐arylmaleimide or ‐phthalimide **4** to produce a highly f