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One-Pot Stereoselective Synthesis of trans-4,5-Dialkoxy-1,3-bis(2-pyrimidinyl)imidazolidines Through a Three-Component Reaction.

✍ Scribed by Mehdi Ghandi; Farshid Salimi; Abolfazl Olyaei


Publisher
John Wiley and Sons
Year
2006
Weight
15 KB
Volume
37
Category
Article
ISSN
0931-7597

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One-Pot stereoselective synthesis of tra
✍ Mehdi Ghandi; Farshid Salimi; Abolfazl Olyaei πŸ“‚ Article πŸ“… 2006 πŸ› Journal of Heterocyclic Chemistry 🌐 English βš– 238 KB

## Abstract magnified image Stoichiometric reaction of 2‐aminopyrimidine with formaldehyde in the presence of formic acid catalyst in water gave __N,N__′‐bis(2‐pyrimidinyl)methanediamine (**5**). Subsequent cyclocondensation of **5** with glyoxal in alcohol (MeOH, EtOH, PrOH and __i__‐PrOH) under