One-pot synthesis of [14C]arsenobetaine bromide
β Scribed by Martha Bernardo; Kevin Francesconi; Gert Kollenz
- Publisher
- John Wiley and Sons
- Year
- 2004
- Tongue
- French
- Weight
- 85 KB
- Volume
- 47
- Category
- Article
- ISSN
- 0022-2135
- DOI
- 10.1002/jlcr.825
No coin nor oath required. For personal study only.
β¦ Synopsis
Abstract
A oneβpot synthesis of [^14^C]arsenobetaine from 2βdimethylarsinoylacetic acid is described. Cationβ and anionβexchange columns are used in the purification of the compound and its conversion to the bromide salt. Copyright Β© 2004 John Wiley & Sons, Ltd.
π SIMILAR VOLUMES
Benzoquinone-[U-14C] was synthesized in 90% yield from benzene-[U-14C] via a three step oequence. Conditions were developed which allowed this conversion to be accomplished in a one pot closed system. ## The b e n ~o q u i n o n e -[ U -~~C ] thus obtained could be reduced to h y d r o q u i n ~n e
pharmaceutically interesting products in good to excellent yields.
## Abstract Hexadecyltrimethylammonium bromide, a cationic detergent having a wide range of applications, was synthesised from [1β^14^C] hexadecanoic acid __via__ its methyl ester, alcohol and bromide, in an overall yield of 84%. It had a specific activity of 6.30 uCi/mmol and a radiochemical purit