✦ LIBER ✦

“One-pot” Synthesis of 1-Vinyl-2-pyrrolidone with Protic Functional Groups in 3-Position

✍ Scribed by Mónica Pérez Perrino; Rodrigo Navarro; Myriam Gómez Tardajos; Alberto Gallardo; Helmut Reinecke

Publisher: John Wiley and Sons
Year: 2009
Tongue: English
Weight: 216 KB
Volume: 210
Category: Article
ISSN: 1022-1352
DOI: 10.1002/macp.200900306

No coin nor oath required. For personal study only.

✦ Synopsis

Abstract

A synthetic route that allows modification of 1‐vinyl‐2‐pyrrolidone with an alcohol or thiol group in its 3‐position in a one‐pot reaction without using protecting groups is described. The strategy used to achieve this goal is the reaction of the carboxamide anion of 1‐vinyl‐2‐pyrrolidone with cyclic precursors of these functionalities. It is furthermore shown that VP‐monomers functionalized with OH groups are suitable for the preparation of the corresponding copolymers with pure VP. As a second application of the new compounds, we also describe the synthesis of the first asymmetric crosslinker based on VP.

magnified image

📜 SIMILAR VOLUMES

ChemInform Abstract: Stereoselective Syn

ChemInform Abstract: Stereoselective Synthesis of Phenyl-1,2,3-triazoles Containing (E)-Vinyl Halide Group via a One-Pot, Three-Component Reaction.

✍ Wensheng Zhang; Changhui Su; Chunxiang Kuang; Qing Yang 📂 Article 📅 2011 🏛 John Wiley and Sons ⚖ 30 KB 👁 2 views

Synthesis of Functionalized Polymers by

Synthesis of Functionalized Polymers by Means of Living Anionic Polymerization, 2. Synthesis of Well-Defined Chain-End and in-Chain Functionalized Polymers with 1,3-Butadienyl Groups

✍ Naoki Haraguchi; Yoshihiko Sakaguchi; Kenji Sugiyama; Akira Hirao 📂 Article 📅 2001 🏛 John Wiley and Sons 🌐 English ⚖ 153 KB 👁 2 views

Reactions with and in Anydrous Hydrogen

Reactions with and in Anydrous Hydrogen Fluoride, 13. A Convenient One-Pot Synthesis of Glucofurano[2,1-d]oxazolines with an Additional 3,5,6-Orthoester Function

✍ Miethchen, Ralf ;Klein, Holger ;Pedersen, Christian 📂 Article 📅 1994 🏛 John Wiley and Sons 🌐 English ⚖ 358 KB

## Abstract The reactions of dioxolanylium and oxazolinium ions, formed in anhydrous HF from __N__‐acylated 2‐amino‐2‐deoxy‐D‐glucoses and one equivalent of carboxylic acid anhydride or chloride, were investigated by treatment of their HF solutions with triethylamine/alkane or triethylamine/ether s

Condensation of Pyrazol-5-ones Unsubstit

Condensation of Pyrazol-5-ones Unsubstituted in the Position 1 with β-Keto Esters. Synthesis of Pyrano[2,3-c]pyrazol-6-ones.

✍ N. L. Nam; I. I. Grandberg 📂 Article 📅 2006 🏛 John Wiley and Sons ⚖ 19 KB 👁 1 views

Diversity-Oriented Synthesis of Function

Diversity-Oriented Synthesis of Functionalized 1-Aminopyrroles by Regioselective Zinc Chloride-Catalyzed, One-Pot ‘Conjugate Addition/Cyclization’ Reactions of 1,3-Bis(silyl enol ethers) with 1,2-Diaza-1,3-butadienes

✍ Vahuni Karapetyan; Satenik Mkrtchyan; Andreas Schmidt; Orazio A. Attanasi; Gianf 📂 Article 📅 2008 🏛 John Wiley and Sons 🌐 English ⚖ 202 KB 👁 2 views

Synthesis of 1-O-R-5-deoxy-β-D-ribofuran

Synthesis of 1-O-R-5-deoxy-β-D-ribofuranosides with (CH3)2As and (CH3)2AsO as substituents at the 5-position and a methyl or 2′,3′-dihydroxypropyl group as the aglycone in the 1-position

✍ Jinggao Liu; Daniel H. O'Brien; Kurt J. Irgolic 📂 Article 📅 1996 🏛 John Wiley and Sons 🌐 English ⚖ 896 KB

including the naturally occurring (2'R)dimethyl[ l-O-(2',3'-dihydroxypropyl)-5-deoxy-~-~-ribofuranos-5-yl]arsine oxide, were prepared in multi-step reactions from D-ribose and tetramethyldiarsine. The synthetic procedure uses the early substitution of the hydroxy group with bromine at C5, subsequent