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One pot syntheses of thiazol-2-hydrazone, pyridino[2,3-d]pyridazine, pyrazolo[3,4-d]pyridazine, and isoxazolo[4,5-d]pyridazine derivatives

โœ Scribed by Rafat M. Mohareb; Daisy H. Fleita


Publisher
John Wiley and Sons
Year
2002
Tongue
English
Weight
140 KB
Volume
13
Category
Article
ISSN
1042-7163

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โœฆ Synopsis


Abstract

Reactions of the pyridazine derivatives 1aโ€“c with phenyl isothiocyanate followed by heterocyclization with ethyl chloroacetate gave the thiazolidinone derivatives 6aโ€“c. The reactivity of 6a towards some chemical reagents was studied. ยฉ 2002 Wiley Periodicals, Inc. Heteroatom Chem 13:258โ€“262, 2002; Published online in Wiley Interscience (www.interscience.wiley.com). DOI 10.1002/hc.10026


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Regioselective synthesis of some novel p
โœ Mohamed R. Shaaban; Ahmad M. Farag; Tamer S. Saleh; Fayez H. Osman ๐Ÿ“‚ Article ๐Ÿ“… 2007 ๐Ÿ› Journal of Heterocyclic Chemistry ๐ŸŒ English โš– 383 KB

The latter compound reacts regioselectively with some nitrilimines and nitrile oxides to afford the corresponding pyrazole and isoxazole derivatives, respectively. These reaction products react with hydrazine hydrate to give the novel pyrazolo [3,4-d]pyridazine and isoxazolo [3,4-d]pyridazine deriva