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One-pot regioselective vinylation of tetrazoles: preparation of 5-substituted 2-vinyl-2H-tetrazoles

✍ Scribed by Jaroslav Roh; Kateřina Vávrová; Alexandr Hrabálek

Publisher
Elsevier Science
Year
2010
Tongue
French
Weight
289 KB
Volume
51
Category
Article
ISSN
0040-4039

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Novel regioselective N-alkylations of 5-
Novel regioselective N-alkylations of 5-substituted-2H-tetrazoles
✍ Marija Prhavc; Jozˇe Kobe 📂 Article 📅 1990 🏛 Elsevier Science 🌐 French ⚖ 178 KB

Regioselective alkylation of 5-substituted-2H-tetrazoles 1 to 2-alkyl derivatives 3 was achieved via decarboxylative alkylation with alkyl cyanoformates. Lesser selectivity was observed with chloroformates.