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One-Pot Racemization Process of 1-Phenyl-1,2,3,4-tetrahydroisoquinoline: A Key Intermediate for the Antimuscarinic Agent Solifenacin

✍ Scribed by Bolchi, Cristiano; Pallavicini, Marco; Fumagalli, Laura; Straniero, Valentina; Valoti, Ermanno


Book ID
120024103
Publisher
American Chemical Society
Year
2013
Tongue
English
Weight
283 KB
Volume
17
Category
Article
ISSN
1083-6160

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ChemInform Abstract: Synthetic Studies o
✍ T. MURAKAMI; T. SHIMIZU πŸ“‚ Article πŸ“… 2010 πŸ› John Wiley and Sons βš– 35 KB πŸ‘ 1 views

Synthetic Studies on Sphingolipids. Part 4. Improved Synthesis of (4S)-4-[(1S,2R)-1,2-Epoxybut-3-enyl]-2-phenyl-2-oxazoline, a Key Intermediate for Sphingolipids. -A novel route to the title compound (VIII) is reported with an oxidative bromination [(VI) β†’ (VII)] as the key step.