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One-pot procedure for the preparation of 14C -labelled trisodium phosphonoformate hexahydrate (foscarnet)

✍ Scribed by Lars Gawell

Publisher: John Wiley and Sons
Year: 1983
Tongue: French
Weight: 122 KB
Volume: 20
Category: Article
ISSN: 0022-2135
DOI: 10.1002/jlcr.2580200706

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✦ Synopsis

Trisodium phosphono[ 1 4 C ] formate i s synthesized from [ 14Cjphosgene i n 4 steps. A l l r e a c t i o n s are performed i n s i t u i n an o v e r a l l radiochemical y i e l d o f 51%.

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