✦ LIBER ✦
A method for the preparation of 14C-labeled carboxylic acids. Synthesis of 6,11-dihydro[b,e]thiepin-11-one-3-yl acetic 14C-acid
✍ Scribed by Howard Parnes
- Publisher
- John Wiley and Sons
- Year
- 1979
- Tongue
- French
- Weight
- 198 KB
- Volume
- 16
- Category
- Article
- ISSN
- 0022-2135
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✦ Synopsis
Abstract
An example of a potentially general method for the preparation of ^14^C‐carboxylic acids based on the carbonation of an α‐lithiated carboxylate is described. This procedure requires only the unlabeled analog of the desired ^14^C‐acid as the precursor. The possibility of carrying out the selective decarboxylation of a malonic acid derivative with loss of only the unlabeled carboxyl group is described.