Mono-N-ethylated h-amino acid esters are obtained in high yields using reductive amination procedures. Formation of imine is achieved by excess of acetaldehyde, followed by removal of acetaldehyde and reduction by NaBH(OAc) 3 . The elaborated one-pot synthesis allows for the efficient synthesis of s
โฆ LIBER โฆ
One Pot N-Protection of Amino Acids
โ Scribed by Chr. Becu; M.-F. Reyniers; M. J. O. Anteunis; R. Callens
- Publisher
- Wiley (John Wiley & Sons)
- Year
- 2010
- Weight
- 243 KB
- Volume
- 99
- Category
- Article
- ISSN
- 0037-9646
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