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One-pot green procedure for Biginelli reaction catalyzed by novel task-specific room-temperature ionic liquids

✍ Scribed by Fang Dong; Luo Jun; Zhou Xinli; Ye Zhiwen; Liu Zuliang


Book ID
103834739
Publisher
Elsevier Science
Year
2007
Tongue
English
Weight
181 KB
Volume
274
Category
Article
ISSN
1381-1169

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✦ Synopsis


Cheap and reusable task-specific ionic liquids that bear an alkanesulfonic acid group in an acyclic trialkylammonium cation were found to be effective catalysts for synthesizing 3,4-dihydropyrimidine-2-(1H)-ones via the one-pot three-component Biginelli reaction. The satisfactory results were obtained with good yields, short reaction time and simplicity in the experimental procedure. The catalysts could be recycled and reused six times without noticeably decrease in the catalytic activity.


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Iodotrimethylsilane-Accelerated One-Pot
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## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.

Iodotrimethylsilane-Accelerated One-Pot
✍ Gowravaram Sabitha; Kusuma B. Reddy; Rangavajjula Srinivas; Jillu S. Yadav 📂 Article 📅 2005 🏛 John Wiley and Sons 🌐 German ⚖ 61 KB 👁 1 views

## Abstract A novel __Biginelli__‐like cyclocondensation reaction is efficiently catalyzed by iodotrimethylsilane (Me~3~SiI) in MeCN. The reaction proceeds at room temperature by a three‐component one‐pot condensation of ketones with aldehydes and urea to afford 5‐unsubstituted 3,4‐dihydropyrimidin