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One-pot construction of isoindolo[2,1-a]quinoline system

✍ Scribed by Shahriar Khadem; Konstantin A. Udachin; Gary D. Enright; Michael Prakesch; Prabhat Arya


Book ID
104096969
Publisher
Elsevier Science
Year
2009
Tongue
French
Weight
385 KB
Volume
50
Category
Article
ISSN
0040-4039

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✦ Synopsis


Polycyclic compounds bearing isoindolo[2,1-a]quinoline system were easily prepared stereo-and regioselectively, and in one-pot, in a tandem fashion containing Povarov's multicomponent and condensation reactions. Involving a stepwise route for the aza Diels-Alder reaction within the synthesis was suggested.


πŸ“œ SIMILAR VOLUMES


Acyliminium ion-olefin cyclization leadi
✍ Pascal Pigeon; Mohamed Othman; Pierre NetchitaΓ―lo; Bernard Decroix πŸ“‚ Article πŸ“… 1999 πŸ› Journal of Heterocyclic Chemistry 🌐 English βš– 320 KB

## Abstract Isoindolo[2,1‐__a__]quinolines 10, 11, 12 were synthesized from hydroxylactams 8 or 9 __via__ an __N__‐acyliminium ion‐π‐olefin nucleophile cyclization reaction.