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Acyliminium ion-olefin cyclization leading to isoindolo[2,1-a]quinoline derivatives
✍ Scribed by Pascal Pigeon; Mohamed Othman; Pierre Netchitaïlo; Bernard Decroix
- Book ID
- 102341331
- Publisher
- Journal of Heterocyclic Chemistry
- Year
- 1999
- Tongue
- English
- Weight
- 320 KB
- Volume
- 36
- Category
- Article
- ISSN
- 0022-152X
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✦ Synopsis
Abstract
Isoindolo[2,1‐a]quinolines 10, 11, 12 were synthesized from hydroxylactams 8 or 9 via an N‐acyliminium ion‐π‐olefin nucleophile cyclization reaction.
📜 SIMILAR VOLUMES
Isoindolo[2, 4] benzodiaze.pinesha-c were synthesized tkom hydroxylactam-acid5 when it was treated successively with thionyl chloride, ammonia (or an alkylamine) and p-tohenesrdfonicacid. @ 1997Elsevier Science Ltd.
## Abstract A one pot synthesis of thienoazepinoisoindolones from the reaction of hydroxylactam‐alcohols, under acidic treatment, is described __via__ an __N__‐acyliminium olefin cyclization.