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Oncomodulin is a macrophage-derived signal for axon regeneration in retinal ganglion cells

โœ Scribed by Yin, Yuqin; Henzl, Michael T; Lorber, Barbara; Nakazawa, Toru; Thomas, Tommy T; Jiang, Fan; Langer, Robert; Benowitz, Larry I

Book ID
109940824
Publisher
Nature Publishing Group
Year
2006
Tongue
English
Weight
518 KB
Volume
9
Category
Article
ISSN
1097-6256

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Retinal ganglion cells (RGCs) in rats were retrogradely labeled with the fluorescent tracer Fluorogold (FG) and subjected to GAP-43 and c-JUN immunocytochemistry to identify those RGCs that are capable of regenerating an axon. After optic nerve section (ONS) and simultaneous application of FG to the