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Oncogenic Transformation of Hamster Embryo Cells in vitro by Adenovirus Type 5

✍ Scribed by WILLIAMS, J. F.

Book ID
109685970
Publisher
Nature Publishing Group
Year
1973
Tongue
English
Weight
431 KB
Volume
243
Category
Article
ISSN
0028-0836

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Transformation of a specific clone of Fischer rat embryo (CREF) cells with wild-type 5 adenovirus (Ad5) or the E1a plus E1b transforming gene regions of Ad5 results in epithelioid transformants that grow efficiently in agar but that do not induce tumors when inoculated into nude mice or syngeneic Fi