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Oncogenic role of DDX3 in breast cancer biogenesis

✍ Scribed by Botlagunta, M; Vesuna, F; Mironchik, Y; Raman, A; Lisok, A; Winnard, P; Mukadam, S; Van Diest, P; Chen, J H; Farabaugh, P

Book ID
109970657
Publisher
Nature Publishing Group
Year
2008
Tongue
English
Weight
409 KB
Volume
27
Category
Article
ISSN
0950-9232

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## Abstract Cumulative evidences show that Runt‐related transcription factor 3 (RUNX3) has a tumor suppressive role in various cancers. In particular, RUNX3 appears to be an important component of the transforming growth factor‐β (TGF‐β)‐induced tumor suppression pathway. Contrary to reports on thi