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Oncogenic function of the MUC1 receptor subunit in gene regulation

โœ Scribed by Kufe, D


Book ID
109972505
Publisher
Nature Publishing Group
Year
2010
Tongue
English
Weight
371 KB
Volume
29
Category
Article
ISSN
0950-9232

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In this study we examined the regulation of expression of the human MUC1 gene in vivo, by developing MUC1 transgenic mice. The data showed that epithelial-specific expression of MUC1 can be directed by just 1.4 kb of 5' flanking sequence using MUC1 cDNA as a reporter gene in vivo. Furthermore, high