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Oncogenetics and minimal residual disease are independent outcome predictors in adult patients with acute lymphoblastic leukemia

✍ Scribed by Beldjord, K.; Chevret, S.; Asnafi, V.; Huguet, F.; Boulland, M.-L.; Leguay, T.; Thomas, X.; Cayuela, J.-M.; Grardel, N.; Chalandon, Y.; Boissel, N.; Schaefer, B.; Delabesse, E.; Cave, H.; Chevallier, P.; Buzyn, A.; Fest, T.; Reman, O.; Vernant, J.-P.; Lheritier, V.; Bene, M. C.; Lafage, M.; Macintyre, E.; Ifrah, N.; Dombret, H.

Book ID
121816830
Publisher
American Society of Hematology
Year
2014
Tongue
English
Weight
941 KB
Volume
123
Category
Article
ISSN
0006-4971

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## Abstract In vivo response to initial therapy, as assessed by determination of minimal residual disease (MRD) after 5 and 12 weeks of treatment, has evolved as a strong prognostic factor in children with acute lymphoblastic leukemia (ALL) treated according to the BFM regime. Individual treatment